Publications
2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006
2005 2004 2003 2002 2001 2000 1999-1993  

 

 

2017

 

 

 

 

Erbeldinger, N., Rapp, F., Ktitareva, S., Wendel, P., Bothe, A.S., Dettmering, T., Durante, M., Friedrich, T., Bertulat, B., Meyer, S., Cardoso, M.C., Hehlgans, S., Rodel, F. and Fournier, C. (2017). Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber. Front Immunol 8, 627.

 

 

Ludwig, A.K., Zhang, P., Hastert, F.D., Meyer, S., Rausch, C., Herce, H.D., Muller, U., Lehmkuhl, A., Hellmann, I., Trummer, C., Storm, C., Leonhardt, H. and Cardoso, M.C. (2017). Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise. Nucleic Acids Res 45, 2438-2457.

 

 

Muster, B., Rapp, A. and Cardoso, M.C. (2017). Systematic analysis of DNA damage induction and DNA repair pathway activation by continuous wave visible light laser micro-irradiation. AIMS Genetics 4(1), 47-68.

 

 

Reinhart, M. and Cardoso, M.C. (2017). A journey through the microscopic ages of DNA replication. Protoplasma (2017) 254, 1151-1162.

 

 

Natale, F., Rapp, A., Yu, W., Maiser, A., Harz, H., Scholl, A., Grulich, S., Anton, T., Horl, D., Chen, W., Durante, M., Taucher-Scholz, G., Leonhardt, H. and Cardoso, M.C. (2017). Identification of the elementary structural units of the DNA damage response. Nat Commun 8, 15760.

 

 

Zhang, P., Rausch, C., Hastert, F.D., Boneva, B., Filatova, A., Patil, S.J., Nuber, U.A., Gao, Y., Zhao, X. and Cardoso, M.C. (2017). Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner. Nucleic Acids Res 45 (12), 7118 - 7136.

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2016

 

 

 

 

Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H., and Cardoso, M.C. (2016). Poly(ADP-ribosyl)ation of Methyl CpG Binding Protein 2 Regulates Chromatin Structure. J Biol Chem 291, 4873-4881.

 

 

Chagin, V.O., Casas-Delucchi, C.S., Reinhart, M., Schermelleh, L., Markaki, Y., Maiser, A., Bolius, J.J., Bensimon, A., Fillies, M., Domaing, P., Rozanov, Y.M., Leonhardt, H., and Cardoso, M.C. (2016). 4D Visualization of replication foci in mammalian cells corresponding to individual replicons. Nat Commun 7, 11231.

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Gracheva, E., Chitale, S., Wilhelm, T., Rapp, A., Byrne, J., Stadler, J., Medina, R., Cardoso, M.C., and Richly, H. (2016). ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair. J Cell Biol 213, 185-200.

 

Lob, D., Lengert, N., Chagin, V.O., Reinhart, M., Casas-Delucchi, C.S., Cardoso, M.C., and Drossel, B. (2016). 3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression. Nat Commun 7, 11207.

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Ludwig, A.K., Zhang, P. and Cardoso, M.C. (2016). Modifiers and Readers of DNA Modifications and their Impact on Genome Structure, Expression and Stability in Disease. Frontiers in Genetics 7, 115.

 

Martin, R.M., Herce, H.D., Ludwig, A.K. and Cardoso, M.C. (2016). Visualization of the Nucleolus in Living Cells with Cell-Penetrating Fluorescent Peptides. Methods Mol Biol 1455, 71-82.

 

Wolf, C., Rapp, A., Berndt, N., Staroske, W., Schuster, M., Dobrick-Mattheuer, M., Kretschmer, S., Konig, N., Kurth, T., Wieczorek, D., Kast, K., Cardoso, M.C., Gunther, C., and Lee-Kirsch, M.A. (2016). RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA. Nat Commun 7, 11752.

 

2015

 

 

 

 

Chagin, V.O., Reinhart, M., and Cardoso, M.C. (2015). High-resolution analysis of Mammalian DNA replication units. Methods Mol Biol 1300, 43-65.

 

 

Helma, J., Cardoso, M.C., Muyldermans, S., and Leonhardt, H. (2015). Nanobodies and recombinant binders in cell biology. J Cell Biol 209, 633-644.

 

 

Jost, K.L., Bertulat, B., Rapp, A., Brero, A., Hardt, T., Domaing, P., Gosele, C., Schulz, H., Hubner, N., and Cardoso, M.C. (2015). Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood. Epigenetics Chromatin 8, 36.

 

 

Kretschmer, S., Wolf, C., Konig, N., Staroske, W., Guck, J., Hausler, M., Luksch, H., Nguyen, L.A., Kim, B., Alexopoulou, D., Dahl, A., Rapp, A., Cardoso, M.C., Shevchenko, A., and Lee-Kirsch, M.A. (2015). SAMHD1 prevents autoimmunity by maintaining genome stability. Ann Rheum Dis 74, e17.

 

 

Lengert, L., Lengert, N., Drossel, B., Cardoso, M. C., Muster, B., Nowak, D. and Rapp, A. (2015). Discrimination of kinetic models by a combination of microirradiation and fluorescence photobleaching. Biophys. J. 109: 1551-1564.

 

 

Martin, R.M., Ter-Avetisyan, G., Herce, H.D., Ludwig, A.K., Lattig-Tunnemann, G., and Cardoso, M.C. (2015). Principles of protein targeting to the nucleolus. Nucleus 6, 314-325.

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Nischan, N., Herce, H.D., Natale, F., Bohlke, N., Budisa, N., Cardoso, M.C., and Hackenberger, C.P. (2015). Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability. Angew Chem Int Ed Engl 54, 1950-1953.

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Rajan, M., Mortusewicz, O., Rothbauer, U., Hastert, F. D., Schmidthals, K., Rapp, A., Leonhardt, H. and Cardoso, M. C. (2015). Generation of an alpaca-derived nanobody recognizing γ-H2AX. FEBS Open Biol 5: 779-788.

 

 

Romero-Fernandez, I., Casas-Delucchi, C.S., Cano-Linares, M., Arroyo, M., Sanchez, A., Cardoso, M.C., and Marchal, J.A. (2015). Epigenetic modifications in sex heterochromatin of vole rodents. Chromosoma 124, 341-351.

 

 

Schumacher, D., Helma, J., Mann, F.A., Pichler, G., Natale, F., Krause, E., Cardoso, M.C., Hackenberger, C.P., and Leonhardt, H. (2015). Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase. Angew Chem Int Ed Engl 54, 13787-13791.

 

 

2014

 

 

Cazzalini, O., Sommatis, S., Tillhon, M., Dutto, I., Bachi, A., Rapp, A., Nardo, T., Scovassi, A.I., Necchi, D., Cardoso, M.C., Stivala, L.A., and Prosperi, E. (2014). CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res 42, 8433-8448.

 

 

Dornblut, C., Quinn, N., Monajambashi, S., Prendergast, L., van Vuuren, C., Münch, S., Deng, W., Leonhardt, H., Cardoso, M.C., Hoischen, C., Diekmann, S., and Sullivan, K.F. (2014). A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle. Open Biol 4, 130229.

 

 

Herce, H.D., Garcia, A.E., and Cardoso, M.C. (2014a). Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules. J Am Chem Soc 136, 17459-17467.

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Herce, H.D., Rajan, M., Lattig-Tunnemann, G., Fillies, M., and Cardoso, M.C. (2014b). A novel cell permeable DNA replication and repair marker. Nucleus 5, 590-600.

 

 

Kind, B., Muster, B., Staroske, W., Herce, H.D., Sachse, R., Rapp, A., Schmidt, F., Koss, S., Cardoso, M.C., and Lee-Kirsch, M.A. (2014). Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutieres syndrome. Hum Mol Genet 23, 5950-5960.

 

 

Sansoni, V., Casas-Delucchi, C.S., Rajan, M., Schmidt, A., Bonisch, C., Thomae, A.W., Staege, M.S., Hake, S.B., Cardoso, M.C., and Imhof, A. (2014). The histone variant H2A.Bbd is enriched at sites of DNA synthesis. Nucleic Acids Res 42, 6405-6420.

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Smirnov, E., Borkovec, J., Kovacik, L., Svidenska, S., Schrofel, A., Skalnikova, M., Svindrych, Z., Krizek, P., Ovesny, M., Hagen, G.M., Juda, P., Michalova, K., Cardoso, M.C., Cmarko, D., and Raska, I. (2014). Separation of replication and transcription domains in nucleoli. J Struct Biol 188, 259-266.

 

 

Song, C., Feodorova, Y., Guy, J., Peichl, L., Jost, K.L., Kimura, H., Cardoso, M.C., Bird, A., Leonhardt, H., Joffe, B., and Solovei, I. (2014). DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution. Epigenetics Chromatin 7, 17.

 

 

Wieneke, R., Laboria, N., Rajan, M., Kollmannsperger, A., Natale, F., Cardoso, M.C., and Tampe, R. (2014). Live-cell targeting of his-tagged proteins by multivalent N-nitrilotriacetic acid carrier complexes. J Am Chem Soc 136, 13975-13978.

 

 

2013

 

 

Becker, A., Allmann, L., Hofstatter, M., Casa, V., Weber, P., Lehmkuhl, A., Herce, H.D., and Cardoso, M.C. (2013). Direct homo- and hetero-interactions of MeCP2 and MBD2. PLoS One 8, e53730.

 

 

Brink, M.C., Piebes, D.G., de Groote, M.L., Luijsterburg, M.S., Casas-Delucchi, C.S., van Driel, R., Rots, M.G., Cardoso, M.C., and Verschure, P.J. (2013). A role for MeCP2 in switching gene activity via chromatin unfolding and HP1gamma displacement. PLoS One 8, e69347.

 

 

Herce, H.D., Casas-Delucchi, C.S., and Cardoso, M.C. (2013a). New image colocalization coefficient for fluorescence microscopy to quantify (bio-)molecular interactions. J Microsc 249, 184-194.

 

 

Herce, H.D., Deng, W., Helma, J., Leonhardt, H., and Cardoso, M.C. (2013b). Visualization and targeted disruption of protein interactions in living cells. Nat Commun 4, 2660.

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Hörner, S., Fabritz, S., Herce, H.D., Avrutina, O., Dietz, C., Stark, R.W., Cardoso, M.C., and Kolmar, H. (2013). Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells. Org Biomol Chem 11, 2258-2265.

 

 

Reinhart, M., Casas-Delucchi, C.S., and Cardoso, M.C. (2013). Spatiotemporal visualization of DNA replication dynamics. Methods Mol Biol 1042, 213-225.

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2012

 

 

Bertulat, B., De Bonis, M.L., Della Ragione, F., Lehmkuhl, A., Milden, M., Storm, C., Jost, K.L., Scala, S., Hendrich, B., D'Esposito, M., and Cardoso, M.C. (2012). MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line. PLoS One 7, e47848.

 

 

Cardoso, M.C., Schneider, K., Martin, R.M., and Leonhardt, H. (2012). Structure, function and dynamics of nuclear subcompartments. Curr Opin Cell Biol 24, 79-85.

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Casas-Delucchi, C.S., Becker, A., Bolius, J.J., and Cardoso, M.C. (2012a). Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization. Nucleic Acids Res 40, e176.

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Casas-Delucchi, C.S., van Bemmel, J.G., Haase, S., Herce, H.D., Nowak, D., Meilinger, D., Stear, J.H., Leonhardt, H., and Cardoso, M.C. (2012b). Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin. Nucleic Acids Res 40, 159-169.

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Eskat, A., Deng, W., Hofmeister, A., Rudolphi, S., Emmerth, S., Hellwig, D., Ulbricht, T., Doring, V., Bancroft, J.M., McAinsh, A.D., Cardoso, M.C., Meraldi, P., Hoischen, C., Leonhardt, H., and Diekmann, S. (2012). Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. PLoS One 7, e44717.

 

 

Greinert, R., Volkmer, B., Henning, S., Breitbart, E.W., Greulich, K.O., Cardoso, M.C., and Rapp, A. (2012). UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages. Nucleic Acids Res 40, 10263-10273.

 

 

Jost, K.L., Bertulat, B., and Cardoso, M.C. (2012). Heterochromatin and gene positioning: inside, outside, any side? Chromosoma 121, 555-563.

 

 

Vasiliou, S.A., Ali, F.R., Haddley, K., Cardoso, M.C., Bubb, V.J., and Quinn, J.P. (2012). The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro. Addiction biology 17, 156-170.

 

2011

 

 

Agarwal, N., Becker, A., Jost, K.L., Haase, S., Thakur, B.K., Brero, A., Hardt, T., Kudo, S., Leonhardt, H., and Cardoso, M.C. (2011). MeCP2 Rett mutations affect large scale chromatin organization. Hum Mol Genet 20, 4187-4195.

 

 

Casas-Delucchi, C.S., Brero, A., Rahn, H.P., Solovei, I., Wutz, A., Cremer, T., Leonhardt, H., and Cardoso, M.C. (2011). Histone acetylation controls the inactive X chromosome replication dynamics. Nat Commun 2, 222.

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Casas-Delucchi, C.S., and Cardoso, M.C. (2011). Epigenetic control of DNA replication dynamics in mammals. Nucleus 2, 370-382.

 

 

Frauer, C., Hoffmann, T., Bultmann, S., Casa, V., Cardoso, M.C., Antes, I., and Leonhardt, H. (2011). Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS One 6, e21306.

 

 

Jost, K.L., Haase, S., Smeets, D., Schrode, N., Schmiedel, J.M., Bertulat, B., Herzel, H., Cremer, M., and Cardoso, M.C. (2011a). 3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming. Nucleic Acids Res 39, e113.

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Jost, K.L., Rottach, A., Milden, M., Bertulat, B., Becker, A., Wolf, P., Sandoval, J., Petazzi, P., Huertas, D., Esteller, M., Kremmer, E., Leonhardt, H., and Cardoso, M.C. (2011b). Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies. PLoS One 6, e26499.

 

 

Lattig-Tunnemann, G., Prinz, M., Hoffmann, D., Behlke, J., Palm-Apergi, C., Morano, I., Herce, H.D., and Cardoso, M.C. (2011). Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides. Nat Commun 2, 453.

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Masata, M., Juda, P., Raska, O., Cardoso, M.C., and Raska, I. (2011). A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase. Folia Biol (Praha) 57, 3-11.

 

 

2010

 

 

Baddeley, D., Chagin, V.O., Schermelleh, L., Martin, S., Pombo, A., Carlton, P.M., Gahl, A., Domaing, P., Birk, U., Leonhardt, H., Cremer, C., and Cardoso, M.C. (2010). Measurement of replication structures at the nanometer scale using super-resolution light microscopy. Nucleic Acids Res 38, e8.

 

 

Chagin, V.O., Stear, J.H., and Cardoso, M.C. (2010). Organization of DNA Replication. In The Nucleus, T. Misteli, and D.L. Spector, eds. (New York: Cold Spring Harbor Laboratory), p. a000737.

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Jaeger, S., Palaniappan, K., Casas-Delucchi, C.S., and Cardoso, M.C. (2010). Classification of cell cycle phases in 3D confocal microscopy using PCNA and chromocenter features. Proceedings of the Seventh Indian Conference on Computer Vision, Graphics and Image Processing ICVGIP '10 412-418.

 

 

Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Casas-Delucchi, C.S., Cardoso, M.C., Leonhardt, H., Hopfner, K.P., and Rothbauer, U. (2010). Modulation of protein properties in living cells using nanobodies. Nat Struct Mol Biol 17, 133-138.

 

 

Martin, R.M., and Cardoso, M.C. (2010). Chromatin condensation modulates access and binding of nuclear proteins. FASEB J 24, 1066-1072.

 

 

Zhu, Y., Wu, Z., Cardoso, M.C., and Parris, D.S. (2010). Processing of lagging strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase. J Virol 84, 7459-7472.

 

 

2009

 

 

Ciobanasu, C., Harms, E., Tünnemann, G., Cardoso, M.C., and Kubitscheck, U. (2009). Cell-penetrating HIV1 TAT peptides float on model lipid bilayers. Biochemistry 48, 4728-4737.

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Ersoy, I., Bunyak, F., Chagin, V., Cardoso, M.C., and Palaniappan, K. (2009). Segmentation and classification of cell cycle phases in fluorescence imaging. Medical image computing and computer-assisted intervention : MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention 12, 617-624.

 

 

Grigaravicius, P., Rapp, A., and Greulich, K.O. (2009). A direct view by immunofluorescent comet assay (IFCA) of DNA damage induced by nicking and cutting enzymes, ionizing (137)Cs radiation, UV-A laser microbeam irradiation and the radiomimetic drug bleomycin. Mutagenesis 24, 191-197.

 

 

Liska, F., Gosele, C., Rivkin, E., Tres, L., Cardoso, M.C., Domaing, P., Krejci, E., Snajdr, P., Lee-Kirsch, M.A., de Rooij, D.G., Kren, V., Krenova, D., Kierszenbaum, A.L., and Hubner, N. (2009). Rat hd mutation reveals an essential role of centrobin in spermatid head shaping and assembly of the head-tail coupling apparatus. Biol Reprod 81, 1196-1205.

 

 

Ter-Avetisyan, G., Tünnemann, G., Nowak, D., Nitschke, M., Herrmann, A., Drab, M., and Cardoso, M.C. (2009). Cell entry of arginine-rich peptides is independent of endocytosis. J Biol Chem 284, 3370-3378.

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Tünnemann, G., and Cardoso, M.C. (2009). Cell-Penetrating Peptides - Uptake, Toxicity and Applications. In Membrane-Active Peptides: Methods and Results on Structure and Function, M. Castanho, ed. (La Jolla, California: IUL Publishers), pp. 331-362.

 

 

Zainol, M., Stoute, J., Almeida, G.M., Rapp, A., Bowman, K.J., Jones, G.D., and Ecvag (2009). Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair. Nucleic Acids Res 37, e150.

 

 

2008

 

 

Görisch, S.M., Sporbert, A., Stear, J.H., Grunewald, I., Nowak, D., Warbrick, E., Leonhardt, H., and Cardoso, M.C. (2008). Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis. Cell Cycle 7, 1983-1990.

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Grünwald, D., Martin, R.M., Buschmann, V., Bazett-Jones, D.P., Leonhardt, H., Kubitscheck, U., and Cardoso, M.C. (2008). Probing intranuclear environments at the single-molecule level. Biophys J 94, 2847-2858.

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Gupta, S., Höpner, S., Rupp, B., Günther, S., Dickhaut, K., Agarwal, N., Cardoso, M.C., Kühne, R., Wiesmüller, K.H., Jung, G., Falk, K., and Rötzschke, O. (2008). Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules. PLoS One 3, e1814.

 

 

Mortusewicz, O., Leonhardt, H., and Cardoso, M.C. (2008a). Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites. J Cell Biochem 104, 1562-1569.

 

 

Mortusewicz, O., Roth, W., Li, N., Cardoso, M.C., Meisterernst, M., and Leonhardt, H. (2008b). Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites. J Cell Biol 183, 769-776.

 

 

Nitschke, M., Korte, T., Tielesch, C., Ter-Avetisyan, G., Tünnemann, G., Cardoso, M.C., Veit, M., and Herrmann, A. (2008). Equine arteritis virus is delivered to an acidic compartment of host cells via clathrin-dependent endocytosis. Virology 377, 248-254.

 

 

Rothbauer, U., Zolghadr, K., Muyldermans, S., Schepers, A., Cardoso, M.C., and Leonhardt, H. (2008). A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Mol Cell Proteomics 7, 282-289.

 

 

Rottach, A., Kremmer, E., Nowak, D., Boisguerin, P., Volkmer, R., Cardoso, M.C., Leonhardt, H., and Rothbauer, U. (2008a). Generation and characterization of a rat monoclonal antibody specific for PCNA. Hybridoma (Larchmt) 27, 91-98.

 

 

Schermelleh, L., Carlton, P.M., Haase, S., Shao, L., Winoto, L., Kner, P., Burke, B., Cardoso, M.C., Agard, D.A., Gustafsson, M.G., Leonhardt, H., and Sedat, J.W. (2008). Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science 320, 1332-1336.

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Shumaker, D.K., Solimando, L., Sengupta, K., Shimi, T., Adam, S.A., Grünwald, A., Strelkov, S.V., Aebi, U., Cardoso, M.C., and Goldman, R.D. (2008). The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol 181, 269-280.

 

 

Tünnemann, G., Ter-Avetisyan, G., Martin, R.M., Stöckl, M., Herrmann, A., and Cardoso, M.C. (2008). Live-cell analysis of cell penetration ability and toxicity of oligo-arginines. J Pept Sci 14, 469-476.

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Zolghadr, K., Mortusewicz, O., Rothbauer, U., Kleinhans, R., Goehler, H., Wanker, E.E., Cardoso, M.C., and Leonhardt, H. (2008). A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells. Mol Cell Proteomics 7, 2279-2287.

 

 

2007

 

 

Agarwal, N., Hardt, T., Brero, A., Nowak, D., Rothbauer, U., Becker, A., Leonhardt, H., and Cardoso, M.C. (2007). MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation. Nucleic Acids Res 35, 5402-5408.

 

 

Easwaran, H.P., Leonhardt, H., and Cardoso, M.C. (2007). Distribution of DNA replication proteins in Drosophila cells. BMC Cell Biol 8, 42.

 

 

Martin, R.M., Görisch, S.M., Leonhardt, H., and Cardoso, M.C. (2007a). An unexpected link between energy metabolism, calcium, chromatin condensation and cell cycle. Cell Cycle 6, 2422-2424.

 

 

Martin, R.M., Tünnemann, G., Leonhardt, H., and Cardoso, M.C. (2007b). Nucleolar marker for living cells. Histochem Cell Biol 127, 243-251.

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Schermelleh, L., Haemmer, A., Spada, F., Rösing, N., Meilinger, D., Rothbauer, U., Cardoso, M.C., and Leonhardt, H. (2007). Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res 35, 4301-4312.

 

 

Tünnemann, G., Karczewski, P., Haase, H., Cardoso, M.C., and Morano, I. (2007). Modulation of muscle contraction by a cell-permeable peptide. J Mol Med 85, 1405-1412.

 

 

Von Vietinghoff, S., Tünnemann, G., Eulenberg, C., Wellner, M., Cardoso, M.C., Luft, F.C., and Kettritz, R. (2007). NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils. Blood 109, 4487-4493.

 

 

2006

 

 

Brero, A., Leonhardt, H., and Cardoso, M.C. (2006). Replication and translation of epigenetic information. Curr Top Microbiol Immunol 301, 21-44.

 

 

Cardoso, M.C. (2006). Fluorescence microscopy: spectral imaging vs. filter-based imaging. In Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, G. D., and K. Ruckpaul, eds. (Berlin: Springer-Verlag), pp. 583-586.

 

 

Görisch, S.M., and Cardoso, M.C. (2006). PCNA and DNA replication (I). In Proliferating Cell Nuclear Antigen, H. Lee, and M. Szyf, eds. (Research SignPost), pp. 51-70.

 

 

Haase, H., Dobbernack, G., Tünnemann, G., Karczewski, P., Cardoso, C., Petzhold, D., Schlegel, W.P., Lutter, S., Pierschalek, P., Behlke, J., and Morano, I. (2006). Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats. FASEB J 20, 865-873.

 

 

Mortusewicz, O., Rothbauer, U., Cardoso, M.C., and Leonhardt, H. (2006). Differential recruitment of DNA Ligase I and III to DNA repair sites. Nucleic Acids Res 34, 3523-3532.

 

 

Perucca, P., Cazzalini, O., Mortusewicz, O., Necchi, D., Savio, M., Nardo, T., Stivala, L.A., Leonhardt, H., Cardoso, M.C., and Prosperi, E. (2006). Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. J Cell Sci 119, 1517-1527.

 

 

Rothbauer, U., Zolghadr, K., Tillib, S., Nowak, D., Schermelleh, L., Gahl, A., Backmann, N., Conrath, K., Muyldermans, S., Cardoso, M.C., and Leonhardt, H. (2006). Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat Methods 3, 887-889.

Movie 1 Movie 2

 

 

Tünnemann, G., Martin, R.M., Haupt, S., Patsch, C., Edenhofer, F., and Cardoso, M.C. (2006). Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J 20, 1775-1784.

 

 

Weidtkamp-Peters, S., Rahn, H.-P., Cardoso, M.C., and Hemmerich, P. (2006). Replication of centromeric heterochromatin in mouse fibroblasts takes place in early, middle, and late S phase. Histochem Cell Biol 125, 91-102.

Movie 1 Movie 2

 

 

2005

 

 

Brero, A., Easwaran, H.P., Nowak, D., Grunewald, I., Cremer, T., Leonhardt, H., and Cardoso, M.C. (2005). Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J Cell Biol 169, 733-743.

Movie 1 Movie 2

 

 

Easwaran, H.P., Leonhardt, H., and Cardoso, M.C. (2005). Cell cycle markers for live cell analyses. Cell Cycle 4, 453-455.

 

 

Grohmann, M., Spada, F., Schermelleh, L., Alenina, N., Bader, M., Cardoso, M.C., and Leonhardt, H. (2005). Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming. BMC Dev Biol 5, 18.

 

 

Grünwald, D., Cardoso, M.C., Leonhardt, H., and Buschmann, V. (2005). Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS). Curr Pharm Biotechnol 6, 381-386.

 

 

Jambor de Sousa, U.L., Kossa, M.D., Fillies, M., Gahl, A., Scheeder, M.R., Cardoso, M.C., Leonhardt, H., Geary, N., Langhans, W., and Leonhardt, M. (2005). CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells. Biochem Biophys Res Commun 338, 757-761.

 

 

Martin, R.M., Leonhardt, H., and Cardoso, M.C. (2005). DNA labeling in living cells. Cytometry A 67, 45-52.

 

 

Mortusewicz, O., Schermelleh, L., Walter, J., Cardoso, M.C., and Leonhardt, H. (2005). Recruitment of DNA methyltransferase I to DNA repair sites. Proc Natl Acad Sci U S A 102, 8905-8909.

 

 

Schermelleh, L., Spada, F., Easwaran, H.P., Zolghadr, K., Margot, J.B., Cardoso, M.C., and Leonhardt, H. (2005). Trapped in action: direct visualization of DNA methyltransferase activity in living cells. Nat Methods 2, 751-756.

 

 

Sporbert, A., Domaing, P., Leonhardt, H., and Cardoso, M.C. (2005). PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins. Nucleic Acids Res 33, 3521-3528.

 

 

2004

 

 

Angus, S.P., Mayhew, C.N., Solomon, D.A., Braden, W.A., Markey, M.P., Okuno, Y., Cardoso, M.C., Gilbert, D.M., and Knudsen, E.S. (2004). RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol Cell Biol 24, 5404-5420.

 

 

 

Cardoso, M.C. (2004). A look at genome duplication in living cells and the development of cell cycle markers. Zellbiologie aktuell 2, 10-11.

 

 

Easwaran, H.P., Schermelleh, L., Leonhardt, H., and Cardoso, M.C. (2004). Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep 5, 1181-1186.

 

 

Sadoni, N., Cardoso, M.C., Stelzer, E.H., Leonhardt, H., and Zink, D. (2004). Stable chromosomal units determine the spatial and temporal organization of DNA replication. J Cell Sci 117, 5353-5365.

 

 

Solomon, D.A., Cardoso, M.C., and Knudsen, E.S. (2004). Dynamic targeting of the replication machinery to sites of DNA damage. J Cell Biol 166, 455-463.

 

 

2003

 

 

Cardoso, M.C. (2003). Law and Order in the Nucleus. Zellbiologie aktuell 29, 8-10.

 

 

Choi, M., Rolle, S., Wellner, M., Cardoso, M.C., Scheidereit, C., Luft, F.C., and Kettritz, R. (2003). Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis. Blood 102, 2259-2267.

 

 

2002

 

 

Cardoso, M.C., and Leonhardt, H. (2002). Protein transduction: a novel tool for tissue regeneration. Biol Chem 383, 1593-1599.

 

 

Derer, W., Easwaran, H.P., Leonhardt, H., and Cardoso, M.C. (2002). A novel approach to induce cell cycle reentry in terminally differentiated muscle cells. FASEB J 16, 132-133.

 

 

Quensel, C., Krämer, J., Cardoso, M.C., and Leonhardt, H. (2002). Smoothelin contains a novel actin cytoskeleton localization sequence with similarity to troponin T. J Cell Biochem 85, 403-409.

 

 

Sporbert, A., Gahl, A., Ankerhold, R., Leonhardt, H., and Cardoso, M.C. (2002). DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. Mol Cell 10, 1355-1365.

 

 

2001

 

 

Kramer, J., Quensel, C., Meding, J., Cardoso, M.C., and Leonhardt, H. (2001). Identification and characterization of novel smoothelin isoforms in vascular smooth muscle. J Vasc Res 38, 120-132.

 

 

Margot, J.B., Cardoso, M.C., and Leonhardt, H. (2001). Mammalian DNA methyltransferases show different subnuclear distributions. J Cell Biochem 83, 373-379.

 

 

2000

 

 

Aguirre-Arteta, A.M., Grunewald, I., Cardoso, M.C., and Leonhardt, H. (2000). Expression of an alternative Dnmt1 isoform during muscle differentiation. Cell Growth Differ 11, 551-559.

 

 

Leonhardt, H., and Cardoso, M.C. (2000). DNA methylation, nuclear structure, gene expression and cancer. J Cell Biochem Suppl Suppl 35, 78-83.

 

 

Leonhardt, H., Rahn, H.-P., Weinzierl, P., Sporbert, A., Cremer, T., Zink, D., and Cardoso, M.C. (2000a). Dynamics of DNA replication factories in living cells. J Cell Biol 149, 271-280.

 

 

Leonhardt, H., Sporbert, A., and Cardoso, M.C. (2000b). Targeting regulatory factors to intranuclear replication sites. Crit Rev Eukaryot Gene Expr 10, 127-133.

 

 

Margot, J.B., Aguirre-Arteta, A.M., Di Giacco, B.V., Pradhan, S., Roberts, R.J., Cardoso, M.C., and Leonhardt, H. (2000). Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure. J Mol Biol 297, 293-300.

 

 

1999-1993

 

 

Cardoso, M.C., and Leonhardt, H. (1999a). Differentiation, development and programmed cell death. In The Molecular Basis of Cell Cycle and Growth control, G. Stein, R. Baserga, D. Denhardt, and A. Giordano, eds. (New York: John Wiley & Sons), pp. 305-347.

 

 

Cardoso, M.C., and Leonhardt, H. (1999b). DNA methyltransferase is actively retained in the cytoplasm during early development. J Cell Biol 147, 25-32.

 

 

Cardoso, M.C., Sporbert, A., and Leonhardt, H. (1999). Structure and function in the nucleus: subnuclear trafficking of DNA replication factors. J Cell Biochem Suppl 32-33, 15-23.

 

 

Derer, W., Easwaran, H.P., Knopf, C.W., Leonhardt, H., and Cardoso, M.C. (1999). Direct protein transfer to terminally differentiated muscle cells. J Mol Med 77, 609-613.

 

 

Engel, F.B., Hauck, L., Cardoso, M.C., Leonhardt, H., Dietz, R., and von Harsdorf, R. (1999). A mammalian myocardial cell-free system to study cell cycle reentry in terminally differentiated cardiomyocytes. Circ Res 85, 294-301.

 

 

Kramer, J., Aguirre-Arteta, A.M., Thiel, C., Gross, C.M., Dietz, R., Cardoso, M.C., and Leonhardt, H. (1999). A novel isoform of the smooth muscle cell differentiation marker smoothelin. J Mol Med 77, 294-298.

 

 

Lee-Kirsch, M.A., Gaudet, F., Cardoso, M.C., and Lindpaintner, K. (1999). Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing. Circ Res 84, 240-246.

 

 

Leonhardt, H., Rahn, H.-P., and Cardoso, M.C. (1999). Functional links between nuclear structure, gene expression, DNA replication, and methylation. Crit Rev Eukaryot Gene Expr 9, 345-351.

 

 

von Harsdorf, R., Hauck, L., Mehrhof, F., Wegenka, U., Cardoso, M.C., and Dietz, R. (1999). E2F-1 overexpression in cardiomyocytes induces downregulation of p21CIP1 and p27KIP1 and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I. Circ Res 85, 128-136.

 

 

Cardoso, M.C., and Leonhardt, H. (1998). Protein targeting to subnuclear higher order structures: a new level of regulation and coordination of nuclear processes. J Cell Biochem 70, 222-230.

 

 

Leonhardt, H., Rahn, H.-P., and Cardoso, M.C. (1998). Intranuclear targeting of DNA replication factors. J Cell Biochem Suppl 30-31, 243-249.

 

 

Cardoso, M.C., Joseph, C., Rahn, H.-P., Reusch, R., Nadal-Ginard, B., and Leonhardt, H. (1997). Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo. J Cell Biol 139, 579-587.

 

 

Cardoso, M.C., and Leonhard, H. (1995). Immunofluorescence techniques in cell cycle studies. In Cell Cycle: Materials and Methods, M. Pagano, ed. (Heidelberg: Springer Verlag), pp. 15-28.

 

 

Leonhardt, H., and Cardoso, M.C. (1995). Targeting and association of proteins with functional domains in the nucleus: the insoluble solution. In Structural and Functional Organization of the Nuclear Matrix. Int Rev Cytol 162B, 303-335.

 

 

Cardoso, M.C., Leonhardt, H., and Nadal-Ginard, B. (1993). Reversal of terminal differentiation and control of DNA replication: cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication. Cell 74, 979-992.

 

 

McDermott, J.C., Cardoso, M.C., Yu, Y.T., Andres, V., Leifer, D., Krainc, D., Lipton, S.A., and Nadal-Ginard, B. (1993). hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors. Mol Cell Biol 13, 2564-2577.
 
 
     
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